A Large-Scale Medical Sequencing Clinical Research Pilot Study

ClinSeq is a pilot clinical genomics research study designed to develop infrastructure for generating whole genome sequencing (WGS) data from individual patients. This data is analyzed and interpreted to discover associations between genes (genotypes) and physical characteristics (phenotypes). Additionally, ClinSeq also evaluates the return of genomic results to individual patients.

ClinSeq has enrolled over 900 participants and aims to enroll 1500 participants in the project. Each participant has a clinical visit and is tested for heart health. Participants also provide information on family and medical histories. Additionally, blood samples are taken for routine tests to look for health problems such as diabetes, high cholesterol and is used for genetic testing. The project seeks to learn about the role that genes play in a patient's health.